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Board of Directors

David F. Hale is one of our co-founders and has served as Executive Chairman of our Board of Directors since December 2007. Mr. Hale served as our Interim CEO from January 2008 to August 2008 and as Non-Executive Chairman of our Board from August 2003 to December 2007. Mr. Hale is Chairman and Chief Executive Officer of Hale BioPharma Ventures. He served as President and Chief Executive Officer and a director of CancerVax Corporation, from October 2000 through its merger with Micromet, Inc., in 2006 where he became Chairman. He was President and Chief Executive Officer and a director of Women First HealthCare, Inc., from January 1998 to May 2000. Mr. Hale served as President, Chief Executive Officer, Chairman and a director of Gensia Inc., which merged to become Gensia Sicor, from May 1987 to November 1997. Prior to joining Gensia, Mr. Hale was President and Chief Executive Officer and a director of Hybritech, Inc., and previously held sales, marketing and general management positions with Johnson & Johnson and Becton Dickinson. Mr. Hale serves as Chairman of the boards of directors of Santarus, Inc., and SkinMedica, Inc., specialty pharmaceutical companies, and Metabasis Therapeutics, Inc., a biopharmaceutical company. He also serves as a director of privately-held biotechnology and specialty pharmaceutical companies including Verus Pharmaceuticals, Inc., and Conatus Pharmaceuticals. Mr. Hale is also a co-founder and member of the boards of directors of industry organizations including BIOCOM/San Diego, the California Healthcare Institute, and CONNECT and is a member of the boards of directors of the Biotechnology Industry Organization and Rady Children's Hospital, the San Diego Economic Development Corporation, and the Biotechnology Institute. Mr. Hale received a Bachelor of Arts degree in Biology and Chemistry from Jacksonville State University.

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Richard W. Pascoe joined Somaxon as our President and Chief Executive Officer in August 2008. Before joining Somaxon, Mr. Pascoe was the Chief Operating Officer at ARIAD Pharmaceuticals, an emerging oncology company, where he led commercial operations, manufacturing, information services, program and alliance management and business development. Mr. Pascoe held a series of senior management roles at King Pharmaceuticals, Inc., including senior vice president of neuroscience marketing and sales and vice president positions in both international sales and marketing and hospital sales. He also held positions in the commercial groups at Medco Research, Inc. (which was acquired by King), COR Therapeutics, Inc. (where he helped lead the successful launch of eptifibatide [Integrilin®]), B. Braun Interventional and the BOC Group. Mr. Pascoe served as a commissioned officer in the United States Army following his graduation from the United States Military Academy at West Point where he received a B.S degree in Leadership.

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Terrell A. Cobb has served as a member of our board of directors since August 2003. Mr. Cobb is the founder and currently serves as President of ProCom One, a position he has held since 1998. From 1995 to the present, Mr. Cobb has served as a consultant focusing on business development activities in the pharmaceutical industry. Mr. Cobb previously spent 15 years in various positions at Johnson and Johnson. Mr. Cobb has founded four specialty pharmaceutical companies, has held senior management positions in several start-up organizations, including Pharmaco and Scandipharm, and has acted as an advisor and consultant to other drug development companies.

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Michael L. Eagle has served on our board of directors since May of 2007. He served as Vice President of Manufacturing for Eli Lilly and Company from 1994 through 2001 and held a number of executive management positions with Eli Lilly and its subsidiaries throughout his career there. Mr. Eagle serves as chairman of the board of directors of Favrille, Inc., and serves on the boards of directors of Micrus Endovascular Corporation, XTENT, Inc, and a number of privately-held companies. Mr. Eagle earned a Bachelor of Science degree in mechanical engineering from Kettering University and an MBA from the Krannert School of Management at Purdue University . He serves on the Board of Trustees of Kettering University, on the Dean's Senior Advisory Council of the Krannert School of Management at Purdue University.

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Erle T. Mast has served on our board of directors since June 2008. Mr. Mast was Chief Financial Officer of Pharmion Corporation from 2002 until its acquisition by Celgene Corporation in March 2008. Mr. Mast was also an Executive Vice President of Pharmion from February 2006 until the acquisition. He was Vice President of Finance for Dura Pharmaceuticals, Inc. from 1997 until its acquisition by Elan Corporation, plc in 2000, and thereafter he was Chief Financial Officer of Elan's Global Biopharmaceuticals business until 2002. Prior to that, Mr. Mast was a partner with Deloitte & Touche, LLP. Mr. Mast graduated from California State University Bakersfield with a degree in business administration.

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Jesse I. Treu, Ph.D. , has been a Partner of Domain since its inception 22 years ago. He has been a director of over 30 early-stage health care companies, 18 of which have so far become successful public companies. Present board memberships include Altea Therapeutics, Aesthetic Sciences, BiPar Sciences, CoLucid, Regado Biosciences, SenoRx and Somaxon Pharmaceuticals. Past board memberships include Biosite Diagnostics, Dianon Systems, DNX, GelTex Pharmaceuticals, Inspire Pharmaceuticals, Iomai, Lumisys, NPS Pharmaceuticals, Northstar Neuroscience, OraPharma, Sepracor, Trimeris and Viagene. He has served as a Founder, President and Chairman of numerous venture stage companies. Prior to the formation of Domain, Dr. Treu had 12 years of experience in the health care industry. Dr. Treu was V.P. of the predecessor organization to The Wilkerson Group, and its venture capital arm, CW Ventures. While at CW Ventures, he served as President and CEO of Microsonics, a pioneer in computer image processing for cardiology. From 1977 through 1982, Dr. Treu led new product development and marketing planning for immunoassay and histopathology products at Technicon Corporation (now Siemens Medical Solutions Diagnostics). Dr. Treu began his career with GE in 1973, initially as a research scientist developing thin film optical sensors for immunoassay testing, and subsequently serving on the corporate staff with responsibility for technology assessment and strategic planning. Dr. Treu received his B.S. from Rensselaer Polytechnic Institute and from Princeton University his M.A. and Ph.D. degrees in physics.

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Daniel K. Turner III has served as a member of our board of directors since April 2004. Mr. Turner is a General Partner of Montreux Equity Partners, a position he has held since February 1993. Mr. Turner has 20 years of experience as an entrepreneur, operating manager and venture capitalist. Prior to Montreux, Mr. Turner managed the Turnaround Group for Berkeley International. Previously, Mr. Turner was the founding Chief Financial Officer of Oclassen Pharmaceuticals, Inc., which merged with Watson Pharmaceuticals. Mr. Turner started his career with Price Waterhouse in the high technology group. Mr. Turner holds a B.S. degree from Sacramento State University and attended the MBA program at the Haas School of Business at the University of California , Berkeley , where he has established the Turner Fellowship. Mr. Turner is a Certified Public Accountant.

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Kurt von Emster, CFA, has served as a member of our board of directors since August 2005. Mr. von Emster is a General Partner of MPM Capital, a position he has held since November 2000, and serves as Portfolio Manager for the MPM BioEquities Fund. Prior to joining MPM, Mr. von Emster spent 11 years with Franklin Templeton Group as a Vice President and Portfolio Manager. Mr. von Emster holds the Chartered Financial Analyst designation (CFA), is a member of the Association for Investment Management and Research and is a member of the Security Analysts of San Francisco. He has a degree from the University of California at Santa Barbara in Business and Economics.

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Kurt C. Wheeler has served as a member of our board of directors since June 2005. Mr. Wheeler is a Managing Director of Clarus Ventures, a venture capital firm, a position he has held since February 2005, and is a General Partner of MPM Capital BioVentures II and III funds, a position he has held since March 2000. He serves on the boards of directors of Alsius, Inc., HemoSense, Inc., and CryoCor, Inc., as well as a number of private medical device and biopharmaceutical companies. He began his professional career at Eli Lilly & Co. He holds a B.A. from Brigham Young University and a M.B.A. from Northwestern University.

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Thomas G. Wiggans has served on our board of directors since June 2008. Mr. Wiggans served as Chief Executive Officer of Connetics Corporation from 1994 until December 2006 when Connetics was acquired by Stiefel Laboratories, Inc. Mr. Wiggans was also Chairman of the Board of Connetics from January 2006 until the acquisition. From 1992 to 1994, Mr. Wiggans served as President and Chief Operating Officer of CytoTherapeutics Inc. He served in various positions at Ares-Serono Group from 1980 to 1992, including President of its U.S. pharmaceutical operations and Managing Director of its U.K. pharmaceutical operations. Mr. Wiggans currently serves as Chairman of the Board of Peplin, Inc. and on the board of directors of Sangamo Biosciences, Inc. and Onyx Pharmaceuticals, Inc. He is also on the Board of Overseers of the Hoover Institution at Stanford University and the Board of Trustees of the University of Kansas Endowment Association . In addition, Mr. Wiggans is Chairman of the Biotechnology Institute, a non-profit educational organization. Mr. Wiggans holds a B.S. in Pharmacy from the University of Kansas and an M.B.A. from Southern Methodist University.

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